Esomeprazole is the S-isomer of omeprazole and reduces gastric acid secretion through a specific targeted mechanism of action. It is a specific inhibitor of the acid pump in the parietal cell. Both the R- and S-isomer of omeprazole have similar pharmacodynamic activity
Each capsule contains: Esomeprazole 20mg (as Esomeprazole Magnesium Trihydrate in delayed release form). Esomeprazole 40mg (as Esomeprazole Magnesium Trihydrate in delayed release form).
In combination with antibiotics in treatment of duodenal ulcer caused by Helicobacter pylori.
DOSAGE & ADMINISTRATION:
Dose adjustment is not required in patients with impaired renal function. Due to limited experience in patients with severe renal insufficiency, such patients should be treated with caution, Impaired hepatic function Dose adjustment is not required in patients with mild to moderate liver impairment. For patients with severe liver impairment, a maximum dose of 20 mg AXESOM should not be exceeded.
Known hypersensitivity to esomeprazole, substituted benzimidazoles or any other constituents of the formulation. Esomeprazole should not be used concomitantly with nelfinavir.
1. Axesom 20mg Capsules: Blister pack of 2x7’s. 2. Axesom 40mg Capsules: Blister pack of 2x7’s.