NEBIX contains Nebivolol Hydrochloride.
NEBIX range is available for oral administration. 1. NEBIX 2.5mg tablets: Each film coated tablet contains Nebivolol (as HCl) 2.5mg. 2. NEBIX 5mg tablets: Each film coated tablet contains Nebivolol (as HCl) 5mg. 3. NEBIX 10mg tablets: Each film coated tablet contains Nebivolol (as HCl) 10mg.
NEBIX is indicated for the treatment of hypertension & treatment of stable mild and moderate chronic heart failure.
DOSAGE & ADMINISTRATION:
Hypertension: The starting dose of NEBIX is 5mg once daily in most patients preferably at the same time of the day. Individualize to the need of the patient for up-titration with two weeks interval. NEBIX can be taken with or without food. Heart Failure: The initial up-titration should be done according to the following steps at 1-2 weekly intervals based on patient tolerability: NEBIX1.25 mg to be increased to 2.5 mg once daily, then to 5 mg once daily and then to 10 mg once daily. The maximum recommended dose is 10 mg nebivolol once daily.
Nebivolol is contraindicated in severe bradycardia, heart block greater than first degree, patients with cardiogenic shock, decompensated cardiac failure, sick sinus syndrome (unless a permanent pacemaker is in place), patients with severe hepatic impairment (Child-Pugh >B) and hypersensitive to any component of this product.
NEBIX 2.5mg, NEBIX 5mg & NEBIX 10mg, each film coated tablet contains Nebivolol Hydrochloride 2.5mg, 5mg & 10mg respectively, all are available in Alu-Alu Blister pack of 14’s.
PREGNANCY & LACTATION:
NEBIX should not be used during pregnancy and in lactating mothers.